Version 5.4
Homo sapiens Gene: DAPP1
Summary
InnateDB Gene IDBG-31523.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DAPP1
Gene Name dual adaptor of phosphotyrosine and 3-phosphoinositides
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000070190
Encoded Proteins
IDBP-31525
dual adaptor of phosphotyrosine and 3-phosphoinositides
IDBP-477070
dual adaptor of phosphotyrosine and 3-phosphoinositides
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 4:99816833-99870154
Strand Forward strand
Band q23
Transcripts
ENST00000296414 ENSP00000296414
ENST00000512369 ENSP00000423602
ENST00000507994
ENST00000514301
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005543 phospholipid binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
Biological Process
GO:0006470 protein dephosphorylation
GO:0007165 signal transduction
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028159
View Gene Order
ENSBTAG00000007921
Not yet available
Pathways
NETPATH
NetPath_4
EGFR1 pathway
NetPath_12
BCR pathway
NetPath_24
TSLP pathway
REACTOME
REACT_118700
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_118773
Signaling by the B Cell Receptor (BCR) pathway
KEGG
hsa04662
B cell receptor signaling pathway pathway
INOH
INOH website
B cell receptor signaling pathway
PID NCI
pi3kcipathway
Class I PI3K signaling events
bcr_5pathway
BCR signaling pathway
Cross-References
SwissProt Q9UN19
TrEMBL J3KNB3
UniProt Splice Variant
Entrez Gene 27071
UniGene Hs.708484
RefSeq NM_014395
HUGO HGNC:16500
OMIM 605768
CCDS CCDS47112
HPRD
IMGT
EMBL AF161551 AF163254 AF178987 AF186022 AL713793 AP001962 BC012924 CH471057
GenPept AAD49697 AAF14578 AAF29038 AAF44351 AAH12924 CAD28547 EAX06111
RNA Seq Atlas 27071

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca