Version 5.4
Mus musculus Gene: Lhx9
Summary
InnateDB Gene IDBG-196080.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lhx9
Gene Name LIM homeobox protein 9
Synonyms 3110009O07Rik; BB104635; LH2B
Species Mus musculus
Ensembl Gene ENSMUSG00000019230
Encoded Proteins
IDBP-196082
LIM homeobox protein 9
IDBP-196084
LIM homeobox protein 9
IDBP-196086
LIM homeobox protein 9
IDBP-256869
LIM homeobox protein 9
IDBP-256871
LIM homeobox protein 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143355:
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:138825186-138848576
Strand Reverse strand
Band E4
Transcripts
ENSMUST00000093486 ENSMUSP00000091198
ENSMUST00000019374 ENSMUSP00000019374
ENSMUST00000046870 ENSMUSP00000036480
ENSMUST00000112030 ENSMUSP00000107661
ENSMUST00000112026 ENSMUSP00000107657
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0008045 motor neuron axon guidance
GO:0008283 cell proliferation
GO:0008584 male gonad development
GO:0008585 female gonad development
GO:0035262 gonad morphogenesis
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143355
View Gene Order
ENSBTAG00000013499
Not yet available
Cross-References
SwissProt Q9WUH2
TrEMBL
UniProt Splice Variant
Entrez Gene 16876
UniGene Mm.250732
RefSeq NM_010714 XM_006529174 NM_001025565 NM_001042577 XM_006529171 XM_006529172 XM_006529173
OMIM
CCDS CCDS15333 CCDS15334 CCDS35726
HPRD
IMGT
MGI ID MGI:1316721
MGI Symbol Lhx9
EMBL AC154398 AF113518 AF134761 AJ243851 AJ243852 AJ243853 AJ243854 AJ243855 AJ243856 AJ243857 BC072623
GenPept AAD22008 AAD30110 AAH72623 CAB59907 CAB59908 CAB59909
RNA Seq Atlas 16876

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca