Version 5.4
Bos taurus Gene: LHX9
Summary
InnateDB Gene IDBG-638642.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LHX9
Gene Name LIM/homeobox protein Lhx9
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000013499
Encoded Proteins
IDBP-690726
LIM/homeobox protein Lhx9
IDBP-690728
LIM/homeobox protein Lhx9
IDBP-690730
LIM/homeobox protein Lhx9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143355:
This gene encodes a member of the LIM homeobox gene family of developmentally expressed transcription factors. The encoded protein contains a homeodomain and two cysteine-rich zinc-binding LIM domains involved in protein-protein interactions. The protein is highly similar to a mouse protein that causes gonadal agenesis when inactivated, suggesting a role in gonadal development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:78784922-78802807
Strand Forward strand
Band
Transcripts
ENSBTAT00000054943 ENSBTAP00000050628
ENSBTAT00000017945 ENSBTAP00000017945
ENSBTAT00000043591 ENSBTAP00000041150
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0008045 motor neuron axon guidance
GO:0008283 cell proliferation
GO:0008584 male gonad development
GO:0008585 female gonad development
GO:0035262 gonad morphogenesis
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143355
View Gene Order
ENSMUSG00000019230
View Gene Order
Cross-References
SwissProt A0JNI8
TrEMBL Q58CW3
UniProt Splice Variant
Entrez Gene 515012
UniGene Bt.31799
RefSeq XM_005217350 NM_001024544
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126704 BT021834 BT026326 DAAA02043909 DAAA02043910
GenPept AAI26705 AAX46681 ABG81482
RNA Seq Atlas 515012

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca