Mus musculus Gene: Ggt6
Summary
InnateDB Gene IDBG-196707.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ggt6
Gene Name gamma-glutamyltransferase 6
Synonyms 9030405D14Rik; AI427679; AW490214
Species Mus musculus
Ensembl Gene ENSMUSG00000040471
Encoded Proteins
gamma-glutamyltransferase 6
gamma-glutamyltransferase 6
gamma-glutamyltransferase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167741:
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:72435526-72438400
Strand Forward strand
Band B4
Transcripts
ENSMUST00000076443 ENSMUSP00000075773
ENSMUST00000100903 ENSMUSP00000098463
ENSMUST00000108499 ENSMUSP00000104139
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003840 gamma-glutamyltransferase activity
GO:0036374 glutathione hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006749 glutathione metabolic process
GO:0006750 glutathione biosynthetic process
GO:0008150 biological_process
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Glutathione metabolism pathway
Taurine and hypotaurine metabolism pathway
Cyanoamino acid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Glutathione synthesis and recycling pathway
Glutathione conjugation pathway
Aflatoxin activation and detoxification pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
KEGG
Cyanoamino acid metabolism pathway
Taurine and hypotaurine metabolism pathway
Glutathione metabolism pathway
INOH
PID NCI
Cross-References
SwissProt Q6PDE7
TrEMBL A7DTG9 Q7TNR0
UniProt Splice Variant
Entrez Gene 71522
UniGene Mm.23336
RefSeq NM_027819 XM_006534242
OMIM
CCDS CCDS36216
HPRD
IMGT
MGI ID MGI:1918772
MGI Symbol Ggt6
EMBL AK018485 AL662812 BC055837 BC058747
GenPept AAH55837 AAH58747 BAB31233 CAI52002 CAI52003
RNA Seq Atlas 71522