Mus musculus Gene: Lpin2
Summary
InnateDB Gene IDBG-196742.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lpin2
Gene Name lipin 2
Synonyms 2610511G02Rik; AI481352; AW742896
Species Mus musculus
Ensembl Gene ENSMUSG00000024052
Encoded Proteins
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101577:
Mouse studies suggest that this gene functions during normal adipose tissue development and may play a role in human triglyceride metabolism. This gene represents a candidate gene for human lipodystrophy, characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:71182560-71249817
Strand Forward strand
Band E1.3
Transcripts
ENSMUST00000053173
ENSMUST00000142842
ENSMUST00000156570 ENSMUSP00000120634
ENSMUST00000149973
ENSMUST00000129635 ENSMUSP00000119282
ENSMUST00000135589 ENSMUSP00000115061
ENSMUST00000126681 ENSMUSP00000118610
ENSMUST00000130750
ENSMUST00000140150
ENSMUST00000154507 ENSMUSP00000127035
ENSMUST00000133156
ENSMUST00000156565
ENSMUST00000125665
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003713 transcription coactivator activity
GO:0008195 phosphatidate phosphatase activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006629 lipid metabolic process
GO:0006631 fatty acid metabolic process
GO:0016311 dephosphorylation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Synthesis of PE pathway
Synthesis of PC pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Triglyceride Biosynthesis pathway
Glycerophospholipid biosynthesis pathway
Phospholipid metabolism pathway
KEGG
Glycerophospholipid metabolism pathway
Glycerolipid metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Synthesis of PC pathway
Synthesis of PE pathway
Triglyceride Biosynthesis pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism of lipids and lipoproteins pathway
Glycerophospholipid biosynthesis pathway
Cell Cycle pathway
M Phase pathway
Phospholipid metabolism pathway
Mitotic Prophase pathway
Cell Cycle, Mitotic pathway
Metabolism pathway
Depolymerisation of the Nuclear Lamina pathway
Nuclear Envelope Breakdown pathway
KEGG
Glycerophospholipid metabolism pathway
Glycerolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.227924 Mm.446341
RefSeq NM_001164885 NM_022882 XM_006524786 XM_006524787 XM_006524788
OMIM
CCDS CCDS28956 CCDS50177
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas