Version 5.4
Mus musculus Gene: Cux2
Summary
InnateDB Gene IDBG-197822.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cux2
Gene Name cut-like homeobox 2
Synonyms 1700051K22Rik; Cutl2; Cux-2; ENSMUSG00000072641
Species Mus musculus
Ensembl Gene ENSMUSG00000042589
Encoded Proteins
IDBP-197824
cut-like homeobox 2
IDBP-257455
cut-like homeobox 2
IDBP-540221
cut-like homeobox 2
IDBP-538893
cut-like homeobox 2
IDBP-539621
cut-like homeobox 2
IDBP-625485
cut-like homeobox 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000111249:
This gene encodes a protein which contains three CUT domains and a homeodomain; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:121858387-122050102
Strand Reverse strand
Band F
Transcripts
ENSMUST00000086317 ENSMUSP00000083497
ENSMUST00000111752 ENSMUSP00000107381
ENSMUST00000156942 ENSMUSP00000114239
ENSMUST00000133760
ENSMUST00000144069
ENSMUST00000154139 ENSMUSP00000114948
ENSMUST00000134326 ENSMUSP00000120095
ENSMUST00000155396
ENSMUST00000125267
ENSMUST00000168288 ENSMUSP00000130302
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007614 short-term memory
GO:0010628 positive regulation of gene expression
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050775 positive regulation of dendrite morphogenesis
GO:0050890 cognition
GO:0051965 positive regulation of synapse assembly
GO:0061003 positive regulation of dendritic spine morphogenesis
GO:0071310 cellular response to organic substance
GO:2000463 positive regulation of excitatory postsynaptic membrane potential
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000111249
View Gene Order
ENSBTAG00000008571
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.332661 Mm.413594
RefSeq NM_007804 XM_006530154 XM_006530156 XM_006530157 XM_006530158 XM_006530159 XM_006530160
OMIM
CCDS CCDS39251
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca