Version 5.4
Mus musculus Gene: Ikzf4
Summary
InnateDB Gene IDBG-198041.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ikzf4
Gene Name IKAROS family zinc finger 4
Synonyms A630026H08Rik; Eos; Zfpn1a4; Znfn1a4
Species Mus musculus
Ensembl Gene ENSMUSG00000002578
Encoded Proteins
IDBP-198043
IKAROS family zinc finger 4
IDBP-271315
IKAROS family zinc finger 4
IDBP-400312
IKAROS family zinc finger 4
IDBP-536429
IKAROS family zinc finger 4
IDBP-540227
IKAROS family zinc finger 4
IDBP-532114
IKAROS family zinc finger 4
IDBP-535684
IKAROS family zinc finger 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000123411:
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:128630843-128645991
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000065334 ENSMUSP00000066991
ENSMUST00000105233 ENSMUSP00000100866
ENSMUST00000119614 ENSMUSP00000113478
ENSMUST00000133342 ENSMUSP00000114404
ENSMUST00000156052 ENSMUSP00000115337
ENSMUST00000139442 ENSMUSP00000115050
ENSMUST00000153650 ENSMUSP00000115638
ENSMUST00000149762
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006351 transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000123411
View Gene Order
ENSBTAG00000012636
Not yet available
Cross-References
SwissProt Q8C208
TrEMBL
UniProt Splice Variant
Entrez Gene 22781
UniGene Mm.358648 Mm.412767 Mm.488964
RefSeq NM_011772 XM_006513609 XM_006513610 XM_006513611 XM_006513612 XM_006513613 XM_006513614 XM_006513615 XM_006513616
OMIM
CCDS CCDS24284
HPRD
IMGT
MGI ID MGI:1343139
MGI Symbol Ikzf4
EMBL AB017615 AC117232 AK089522 AK170453 BC141286
GenPept AAI41287 BAA36213 BAC40912 BAE41808
RNA Seq Atlas 22781

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca