Version 5.4
Homo sapiens Gene: TRIM50
Summary
InnateDB Gene IDBG-19813.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRIM50
Gene Name tripartite motif containing 50
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146755
Encoded Proteins
IDBP-19815
tripartite motif containing 50
IDBP-377491
tripartite motif containing 50
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 23438823
TRIM50 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:73312539-73328082
Strand Reverse strand
Band q11.23
Transcripts
ENST00000333149 ENSP00000327994
ENST00000453152 ENSP00000413875
ENST00000488217
ENST00000493498
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000053388
View Gene Order
ENSBTAG00000005798
Not yet available
Cross-References
SwissProt Q86XT4
TrEMBL B7ZLG2 D3DXE8 Q2M204
UniProt Splice Variant
Entrez Gene 135892
UniGene Hs.647053
RefSeq NM_001281450 NM_001281451 NM_178125
HUGO HGNC:19017
OMIM 612548
CCDS CCDS34654
HPRD
IMGT
EMBL AC073841 AK292074 AY081948 AY081949 BC112152 BC112154 BC143787 CH471200
GenPept AAI12153 AAI12155 AAI43788 AAL91071 AAL91072 BAF84763 EAW69687 EAW69688 EAW69689 EAW69690 EAW69691
RNA Seq Atlas 135892

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca