Version 5.4
Mus musculus Gene: Trim50
Summary
InnateDB Gene IDBG-203756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trim50
Gene Name tripartite motif-containing 50
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000053388
Encoded Proteins
IDBP-203758
tripartite motif-containing 50
IDBP-258685
tripartite motif-containing 50
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 23438823
[Homo sapiens] TRIM50 was identified in a systematic screen for positive regulators of innate immune responses.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000146755:
Gene Information
Type Protein coding
Genomic Location Chromosome 5:135353295-135368005
Strand Forward strand
Band G2
Transcripts
ENSMUST00000065785 ENSMUSP00000066662
ENSMUST00000111180 ENSMUSP00000106811
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0008152 metabolic process
GO:0070201 regulation of establishment of protein localization
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
GO:0016235 aggresome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000146755
View Gene Order
ENSBTAG00000005798
Not yet available
Cross-References
SwissProt Q810I2
TrEMBL
UniProt Splice Variant
Entrez Gene 215061
UniGene Mm.261834
RefSeq NM_178240 XM_006504411 XM_006504412
OMIM
CCDS CCDS19739
HPRD
IMGT
MGI ID MGI:2664992
MGI Symbol Trim50
EMBL AY081947
GenPept AAL91070
RNA Seq Atlas 215061

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca