Version 5.4
Mus musculus Gene: Crim1
Summary
InnateDB Gene IDBG-198551.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Crim1
Gene Name cysteine rich transmembrane BMP regulator 1 (chordin like)
Synonyms AU015004
Species Mus musculus
Ensembl Gene ENSMUSG00000024074
Encoded Proteins
IDBP-255903
cysteine rich transmembrane BMP regulator 1 (chordin like)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150938:
This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:78200248-78376592
Strand Forward strand
Band E2
Transcripts
ENSMUST00000112498 ENSMUSP00000108117
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004857 enzyme inhibitor activity
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
GO:0030165 PDZ domain binding
Biological Process
GO:0001558 regulation of cell growth
GO:0010951 negative regulation of endopeptidase activity
Cellular Component
GO:0005576 extracellular region
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000150938
View Gene Order
ENSBTAG00000009020
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9JLL0
TrEMBL Q3TWP4
UniProt Splice Variant
Entrez Gene 50766
UniGene Mm.311912 Mm.439091 Mm.474949
RefSeq NM_015800 XM_006524603
OMIM
CCDS CCDS28976
HPRD
IMGT
MGI ID MGI:1354756
MGI Symbol Crim1
EMBL AF168680 AK159603 BC100348
GenPept AAF34410 AAI00349 BAE35222
RNA Seq Atlas 50766

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca