Version 5.4
| Mus musculus Gene: Rdh5 | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-198621.6 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | Rdh5 | ||||||||||
| Gene Name | retinol dehydrogenase 5 | ||||||||||
| Synonyms | 9-cis; AI987873; cRDH; RDH4 | ||||||||||
| Species | Mus musculus | ||||||||||
| Ensembl Gene | ENSMUSG00000025350 | ||||||||||
| Encoded Proteins |
retinol dehydrogenase 5
retinol dehydrogenase 5
retinol dehydrogenase 5
retinol dehydrogenase 5
retinol dehydrogenase 5
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135437:
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 10:128913593-128922888 | ||||||||||
| Strand | Reverse strand | ||||||||||
| Band | D3 | ||||||||||
| Transcripts | |||||||||||
| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
Disease pathway
The canonical retinoid cycle in rods (twilight vision) pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
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| KEGG |
Retinol metabolism pathway
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| INOH | |||||||||||
| PID NCI | |||||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH | |||||||||||
| REACTOME |
The canonical retinoid cycle in rods (twilight vision) pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Visual phototransduction pathway
Disease pathway
The canonical retinoid cycle in rods (twilight vision) pathway
Visual phototransduction pathway
Signal Transduction pathway
Diseases associated with visual transduction pathway
Disease pathway
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| KEGG |
Retinol metabolism pathway
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| INOH | |||||||||||
| PID NCI |
Visual signal transduction: Cones
Visual signal transduction: Rods
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| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Mm.439856 | ||||||||||
| RefSeq | NM_134006 XM_006513385 XM_006513386 XM_006513387 | ||||||||||
| OMIM | |||||||||||
| CCDS | CCDS24298 | ||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| MGI ID | |||||||||||
| MGI Symbol | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||