InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: RDH5

Summary

InnateDB Gene

IDBG-636491.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RDH5

Gene Name

11-cis retinol dehydrogenase

Synonyms

9cRDH

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011927

Encoded Proteins

IDBP-688415

11-cis retinol dehydrogenase

IDBP-688417

11-cis retinol dehydrogenase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135437:
This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene. [provided by RefSeq, Dec 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 5:57858977-57862779

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000065932	ENSBTAP00000056512
ENSBTAT00000022195	ENSBTAP00000022195

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0016491	oxidoreductase activity

Biological Process

GO:0007601	visual perception
GO:0008152	metabolic process
GO:0042572	retinol metabolic process
GO:0050896	response to stimulus
GO:0055114	oxidation-reduction process