Version 5.4
Mus musculus Gene: Rnf123
Summary
InnateDB Gene IDBG-199020.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf123
Gene Name ring finger protein 123
Synonyms BC003945; Kpc1
Species Mus musculus
Ensembl Gene ENSMUSG00000041528
Encoded Proteins
IDBP-199022
ring finger protein 123
IDBP-532307
ring finger protein 123
IDBP-541970
ring finger protein 123
IDBP-540484
ring finger protein 123
IDBP-532047
ring finger protein 123
IDBP-533772
ring finger protein 123
IDBP-535656
ring finger protein 123
IDBP-532627
ring finger protein 123
IDBP-536519
ring finger protein 123
IDBP-626394
ring finger protein 123
IDBP-741781
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164068:
The protein encoded by this gene contains a C-terminal RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions, and an N-terminal SPRY domain. This protein displays E3 ubiquitin ligase activity toward the cyclin-dependent kinase inhibitor 1B which is also known as p27 or KIP1. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:108051534-108083346
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000047746 ENSMUSP00000040803
ENSMUST00000160249 ENSMUSP00000124548
ENSMUST00000162355 ENSMUSP00000125745
ENSMUST00000161673
ENSMUST00000159523
ENSMUST00000159306 ENSMUSP00000125695
ENSMUST00000160649 ENSMUSP00000125495
ENSMUST00000159526
ENSMUST00000159136
ENSMUST00000162123
ENSMUST00000162753 ENSMUSP00000124824
ENSMUST00000160841
ENSMUST00000161828 ENSMUSP00000125213
ENSMUST00000162152
ENSMUST00000162516 ENSMUSP00000124986
ENSMUST00000159372 ENSMUSP00000123933
ENSMUST00000174504 ENSMUSP00000134087
ENSMUST00000178267 ENSMUSP00000136953
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.
Experimentally validated
Total 14 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 10 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0008150 biological_process
GO:0016567 protein ubiquitination
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164068
View Gene Order
ENSBTAG00000011588
Not yet available
Pathways
NETPATH
REACTOME
REACT_236645
Class I MHC mediated antigen processing & presentation pathway
REACT_230745
Immune System pathway
REACT_199115
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_229531
Adaptive Immune System pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75842
Antigen processing: Ubiquitination & Proteasome degradation pathway
REACT_75774
Adaptive Immune System pathway
REACT_6900
Immune System pathway
REACT_75820
Class I MHC mediated antigen processing & presentation pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F6U715
UniProt Splice Variant
Entrez Gene 84585
UniGene Mm.379272 Mm.488389
RefSeq NM_032543 XM_006511877 XM_006511878 XM_006511879 XM_006511880 XM_006511882
OMIM
CCDS CCDS52922
HPRD
IMGT
MGI ID MGI:2148796
MGI Symbol Rnf123
EMBL AC137678
GenPept
RNA Seq Atlas 84585

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca