Version 5.4
Mus musculus Gene: Rgs8
Summary
InnateDB Gene IDBG-199207.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rgs8
Gene Name regulator of G-protein signaling 8
Synonyms 6530413N01Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000042671
Encoded Proteins
IDBP-199209
regulator of G-protein signaling 8
IDBP-257322
regulator of G-protein signaling 8
IDBP-257324
regulator of G-protein signaling 8
IDBP-257326
regulator of G-protein signaling 8
IDBP-257328
regulator of G-protein signaling 8
IDBP-540784
regulator of G-protein signaling 8
IDBP-536037
regulator of G-protein signaling 8
IDBP-534314
regulator of G-protein signaling 8
IDBP-533956
regulator of G-protein signaling 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135824:
This gene is a member of the regulator of G protein signaling (RGS) family and encodes a protein with a single RGS domain. Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. They accelerate transit through the cycle of GTP binding and hydrolysis to GDP, thereby terminating signal transduction, but paradoxically, also accelerate receptor-stimulated activation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:153653025-153700323
Strand Forward strand
Band G3
Transcripts
ENSMUST00000041776 ENSMUSP00000045715
ENSMUST00000111815 ENSMUSP00000107446
ENSMUST00000111814 ENSMUSP00000107445
ENSMUST00000111812 ENSMUSP00000107443
ENSMUST00000111810 ENSMUSP00000107441
ENSMUST00000124500 ENSMUSP00000122518
ENSMUST00000152114 ENSMUSP00000121910
ENSMUST00000147700 ENSMUSP00000123565
ENSMUST00000147482 ENSMUSP00000118365
ENSMUST00000147794
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005096 GTPase activator activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0038032 termination of G-protein coupled receptor signaling pathway
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135824
View Gene Order
ENSBTAG00000026481
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
INOH website
GPCR signaling pathway
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
KEGG
INOH
INOH website
GPCR signaling pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.379143 Mm.396843 Mm.401790
RefSeq NM_026380 XM_006529818 XM_006529819 XM_006529820 XM_006529821 XM_006529822 XM_006529823 XM_006529824 XM_006529825 XM_006529826 XM_006529827 XM_006529828 XM_006529829
OMIM
CCDS CCDS15375
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca