Version 5.4
Mus musculus Gene: Setd1b
Summary
InnateDB Gene IDBG-199221.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Setd1b
Gene Name SET domain containing 1B
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000038384
Encoded Proteins
IDBP-626068
SET domain containing 1B
IDBP-626066
SET domain containing 1B
IDBP-626067
SET domain containing 1B
IDBP-626065
SET domain containing 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139718:
SET1B is a component of a histone methyltransferase complex that produces trimethylated histone H3 at Lys4 (Lee et al., 2007 [PubMed 17355966]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:123142193-123167435
Strand Forward strand
Band F
Transcripts
ENSMUST00000100731
ENSMUST00000056053 ENSMUSP00000134686
ENSMUST00000163030 ENSMUSP00000133933
ENSMUST00000162839 ENSMUSP00000134353
ENSMUST00000174836 ENSMUSP00000134461
ENSMUST00000173221
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003674 molecular_function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0042800 histone methyltransferase activity (H3-K4 specific)
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0051568 histone H3-K4 methylation
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0016607 nuclear speck
GO:0035097 histone methyltransferase complex
GO:0048188 Set1C/COMPASS complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000139718
View Gene Order
ENSBTAG00000004172
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00310
Lysine degradation pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00310
Lysine degradation pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.410967 Mm.418268
RefSeq NM_001040398 XM_006530237 XM_006530238
OMIM
CCDS CCDS59684
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca