Mus musculus Gene: Qpct
Summary
InnateDB Gene IDBG-199418.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Qpct
Gene Name glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
Synonyms 5730422A13Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000024084
Encoded Proteins
glutaminyl-peptide cyclotransferase (glutaminyl cyclase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115828:
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86%% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:79051906-79090243
Strand Forward strand
Band E3
Transcripts
ENSMUST00000040789 ENSMUSP00000038732
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
GO:0008270 zinc ion binding
GO:0016603 glutaminyl-peptide cyclotransferase activity
Biological Process
GO:0006508 proteolysis
GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
Cellular Component
GO:0005576 extracellular region
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.293870
RefSeq NM_027455
OMIM
CCDS CCDS28983
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas