Mus musculus Gene: Kntc1
Summary
InnateDB Gene IDBG-200016.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kntc1
Gene Name kinetochore associated 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000029414
Encoded Proteins
kinetochore associated 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184445:
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. Experimental evidence indicated that the encoded protein functioned in a similar manner to that of the Drosophila rough deal protein. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:123749726-123821593
Strand Forward strand
Band F
Transcripts
ENSMUST00000031366 ENSMUSP00000031366
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0007067 mitotic nuclear division
GO:0007093 mitotic cell cycle checkpoint
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005828 kinetochore microtubule
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8C3Y4
TrEMBL
UniProt Splice Variant
Entrez Gene 208628
UniGene Mm.441089
RefSeq NM_001042421 XM_006530249 XM_006530250 XM_006530251 XM_006530252 XM_006530253 XM_006530254
OMIM
CCDS CCDS39274
HPRD
IMGT
MGI ID MGI:2673709
MGI Symbol Kntc1
EMBL AK084529 AK172905
GenPept BAC39211 BAD32183
RNA Seq Atlas 208628