Mus musculus Gene: Wdr6
Summary
InnateDB Gene IDBG-200295.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wdr6
Gene Name WD repeat domain 6
Synonyms mWDR6
Species Mus musculus
Ensembl Gene ENSMUSG00000066357
Encoded Proteins
WD repeat domain 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178252:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. The encoded protein interacts with serine/threonine kinase 11, and is implicated in cell growth arrest. [provided by RefSeq, Aug 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:108572313-108578670
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000068700 ENSMUSP00000070927
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
Predicted by orthology
Total 14 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0043560 insulin receptor substrate binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007050 cell cycle arrest
GO:0008285 negative regulation of cell proliferation
GO:0010507 negative regulation of autophagy
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0008180 COP9 signalosome
GO:0043234 protein complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q99ME2
TrEMBL Q8CFV1
UniProt Splice Variant
Entrez Gene 83669
UniGene Mm.335454 Mm.481124
RefSeq NM_031392
OMIM
CCDS CCDS23532
HPRD
IMGT
MGI ID MGI:1930140
MGI Symbol Wdr6
EMBL AF348591 AK037181 AK146617 AK163752 BC035951 BC050894 BC054367 CH466560
GenPept AAH35951 AAH50894 AAH54367 AAK31166 BAC29740 BAE27306 BAE37480 EDL21306
RNA Seq Atlas 83669