InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Kcnk1

Summary

InnateDB Gene

IDBG-200794.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Kcnk1

Gene Name

potassium channel, subfamily K, member 1

Synonyms

AI788889; TWIK-1

Species

Mus musculus

Ensembl Gene

ENSMUSG00000033998

Encoded Proteins

IDBP-200796

potassium channel, subfamily K, member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135750:
This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:125995102-126030683

Strand

Forward strand

Band

Transcripts

ENSMUST00000046765

ENSMUSP00000046103

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005244	voltage-gated ion channel activity
GO:0005267	potassium channel activity

Biological Process

GO:0006813	potassium ion transport
GO:0034765	regulation of ion transmembrane transport
GO:0035094	response to nicotine
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0005737	cytoplasm
GO:0005768	endosome
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0016324	apical plasma membrane
GO:0031526	brush border membrane