Version 5.4
Mus musculus Gene: Wls
Summary
InnateDB Gene IDBG-201449.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Wls
Gene Name wntless homolog (Drosophila)
Synonyms 5031439A09Rik; AI173978; AI987742; Gpr177
Species Mus musculus
Ensembl Gene ENSMUSG00000028173
Encoded Proteins
IDBP-201451
wntless homolog (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000116729:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:159839737-159935833
Strand Forward strand
Band H4
Transcripts
ENSMUST00000068952 ENSMUSP00000067898
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0017147 Wnt-protein binding
GO:0031852 mu-type opioid receptor binding
Biological Process
GO:0001707 mesoderm formation
GO:0009948 anterior/posterior axis specification
GO:0016055 Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
Cellular Component
GO:0000139 Golgi membrane
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
GO:0030659 cytoplasmic vesicle membrane
GO:0031410 cytoplasmic vesicle
GO:0032590 dendrite membrane
GO:0032839 dendrite cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000116729
View Gene Order
ENSBTAG00000012976
Not yet available
Pathways
NETPATH
REACTOME
REACT_189085
Disease pathway
REACT_214014
Signaling by Wnt pathway
REACT_213918
WNT ligand biogenesis and trafficking pathway
REACT_233046
Signaling by WNT in cancer pathway
REACT_246422
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_228331
Signaling by WNT in cancer pathway
REACT_11045
Signaling by Wnt pathway
REACT_228014
WNT ligand secretion is abrogated by the PORCN inhibitor LGK974 pathway
REACT_111102
Signal Transduction pathway
REACT_163710
WNT ligand biogenesis and trafficking pathway
REACT_116125
Disease pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q6DID7
TrEMBL
UniProt Splice Variant
Entrez Gene 68151
UniGene Mm.6766
RefSeq NM_026582 XM_006501964
OMIM
CCDS CCDS38684
HPRD
IMGT
MGI ID MGI:1915401
MGI Symbol Wls
EMBL AK019886 AK029053 AK029104 AK044810 AK049842 AK077407 AK159207 BC018381 BC075615
GenPept AAH18381 AAH75615 BAB31904 BAC26266 BAC26300 BAC32102 BAC33950 BAC36788 BAE34898
RNA Seq Atlas 68151

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca