Version 5.4
Mus musculus Gene: Dhx30
Summary
InnateDB Gene IDBG-201735.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Dhx30
Gene Name DEAH (Asp-Glu-Ala-His) box polypeptide 30
Synonyms 2810477H02Rik; C130058C04Rik; Ddx30; HELG; Ret-CoR
Species Mus musculus
Ensembl Gene ENSMUSG00000032480
Encoded Proteins
IDBP-201737
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-201739
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-256940
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-533056
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-540960
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-537790
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-540633
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-532821
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-533355
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-540005
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-537088
DEAH (Asp-Glu-Ala-His) box polypeptide 30
IDBP-627088
DEAH (Asp-Glu-Ala-His) box polypeptide 30
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000132153:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The family member encoded by this gene is a mitochondrial nucleoid protein that associates with mitochondrial DNA. It has also been identified as a component of a transcriptional repressor complex that functions in retinal development, and it is required to optimize the function of the zinc-finger antiviral protein. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:110084320-110117830
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000062368 ENSMUSP00000062622
ENSMUST00000035056 ENSMUSP00000035056
ENSMUST00000111991 ENSMUSP00000107622
ENSMUST00000142911 ENSMUSP00000123122
ENSMUST00000148287 ENSMUSP00000114850
ENSMUST00000127744 ENSMUSP00000121593
ENSMUST00000128979
ENSMUST00000136969 ENSMUSP00000122757
ENSMUST00000148445
ENSMUST00000133529
ENSMUST00000136857
ENSMUST00000149251 ENSMUSP00000119835
ENSMUST00000138940 ENSMUSP00000115980
ENSMUST00000144180 ENSMUSP00000120370
ENSMUST00000149199 ENSMUSP00000122147
ENSMUST00000145932
ENSMUST00000148526
ENSMUST00000128639
ENSMUST00000165596 ENSMUSP00000129174
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003682 chromatin binding
GO:0003725 double-stranded RNA binding
GO:0004386 helicase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008026 ATP-dependent helicase activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006200 ATP catabolic process
GO:0008150 biological_process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0042645 mitochondrial nucleoid
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000132153
View Gene Order
ENSBTAG00000015833
Not yet available
Cross-References
SwissProt Q99PU8
TrEMBL D3YXL7 D3YZM6 D3Z1G8 D3Z2J3
UniProt Splice Variant
Entrez Gene 72831
UniGene Mm.276305 Mm.490120
RefSeq NM_001252682 NM_001252683 NM_133347 XM_006512298 XM_006512299 XM_006512300 XM_006512301 XM_006512302 XM_006512303 XM_006512305 XM_006512306 XM_006512307 XM_006512308 XM_006512309 XM_006512310 XM_006512311 XM_006512312
OMIM
CCDS CCDS23560 CCDS57705 CCDS57706
HPRD
IMGT
MGI ID MGI:1920081
MGI Symbol Dhx30
EMBL AB047557 AC159372 AC161246 AK146326 AK148778 AK153969 BC004082 BC016202
GenPept AAH04082 AAH16202 BAB32789 BAE27081 BAE28661 BAE32286
RNA Seq Atlas 72831

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca