Version 5.4
Mus musculus Gene: Clcnka
Summary
InnateDB Gene IDBG-202042.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Clcnka
Gene Name chloride channel Ka
Synonyms C75963; CLC-K1; Clcnk1
Species Mus musculus
Ensembl Gene ENSMUSG00000033770
Encoded Proteins
IDBP-202044
chloride channel Ka
IDBP-270120
chloride channel Ka
IDBP-532126
chloride channel Ka
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the CLC family of voltage-gated chloride channels. The gene is located adjacent to a highly similar chloride channel gene on chromosome 4. This gene is syntenic with human CLCNKB (geneID:1188). Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:141384610-141398724
Strand Reverse strand
Band D3
Transcripts
ENSMUST00000042617 ENSMUSP00000048520
ENSMUST00000105790 ENSMUSP00000101416
ENSMUST00000150334
ENSMUST00000133676 ENSMUSP00000122396
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005216 ion channel activity
GO:0005247 voltage-gated chloride channel activity
GO:0005515 protein binding
GO:0030554 adenyl nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006821 chloride transport
GO:0034220 ion transmembrane transport
GO:0034765 regulation of ion transmembrane transport
GO:0044070 regulation of anion transport
GO:0050878 regulation of body fluid levels
GO:0055085 transmembrane transport
GO:0072053 renal inner medulla development
GO:1902476 chloride transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0034707 chloride channel complex
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000186510
View Gene Order
Pathways
NETPATH
REACTOME
REACT_196640
Stimuli-sensing channels pathway
REACT_262350
Ion channel transport pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_160189
Stimuli-sensing channels pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.167900
RefSeq NM_001146307 NM_024412
OMIM
CCDS CCDS18871
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca