Version 5.4
Mus musculus Gene: Lamtor1
Summary
InnateDB Gene IDBG-202315.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Lamtor1
Gene Name late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
Synonyms 2400001E08Rik; p18; Pdro
Species Mus musculus
Ensembl Gene ENSMUSG00000030842
Encoded Proteins
IDBP-202317
RIKEN cDNA 2400001E08 gene
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149357:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:101905837-101911901
Strand Forward strand
Band E2
Transcripts
ENSMUST00000033131 ENSMUSP00000033131
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 32 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 32 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
GO:0032947 protein complex scaffold
Biological Process
GO:0001919 regulation of receptor recycling
GO:0007032 endosome organization
GO:0007040 lysosome organization
GO:0010872 regulation of cholesterol esterification
GO:0010874 regulation of cholesterol efflux
GO:0016049 cell growth
GO:0032008 positive regulation of TOR signaling
GO:0032418 lysosome localization
GO:0032439 endosome localization
GO:0034613 cellular protein localization
GO:0042632 cholesterol homeostasis
GO:0043087 regulation of GTPase activity
GO:0043410 positive regulation of MAPK cascade
GO:0043547 positive regulation of GTPase activity
GO:0060620 regulation of cholesterol import
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0031902 late endosome membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045121 membrane raft
GO:0070062 extracellular vesicular exosome
GO:0071986 Ragulator complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000149357
View Gene Order
ENSBTAG00000003001
Not yet available
Cross-References
SwissProt Q9CQ22
TrEMBL
UniProt Splice Variant
Entrez Gene 66508
UniGene Mm.30003 Mm.459636 Mm.460610
RefSeq NM_025605
OMIM
CCDS CCDS21519
HPRD
IMGT
MGI ID MGI:1913758
MGI Symbol Lamtor1
EMBL AK009320 AK013389 AK019947 AK144476 BC020142 BC092062 BC096412 BC115458 BC115459 BC126973
GenPept AAH20142 AAH92062 AAH96412 AAI26974 BAB26214 BAB28825 BAB31928 BAE25909
RNA Seq Atlas 66508

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca