Mus musculus Gene: Cela2a
Summary
InnateDB Gene IDBG-202449.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cela2a
Gene Name chymotrypsin-like elastase family, member 2A
Synonyms Ela-2; Ela2; Ela2a
Species Mus musculus
Ensembl Gene ENSMUSG00000058579
Encoded Proteins
chymotrypsin-like elastase family, member 2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000142615:
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:141814962-141826160
Strand Reverse strand
Band E1
Transcripts
ENSMUST00000102481 ENSMUSP00000099539
ENSMUST00000127962
ENSMUST00000155826
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0017171 serine hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0061436 establishment of skin barrier
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Protein digestion and absorption pathway
Pancreatic secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Pancreatic secretion pathway
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt P05208
TrEMBL
UniProt Splice Variant
Entrez Gene 13706
UniGene Mm.413874 Mm.45316
RefSeq NM_007919
OMIM
CCDS CCDS18884
HPRD
IMGT
MGI ID MGI:95316
MGI Symbol Cela2a
EMBL BC026552 X04573 X04576
GenPept AAH26552 CAA28242 CAA28244
RNA Seq Atlas 13706