Homo sapiens Gene: CELA2A
Summary
InnateDB Gene IDBG-90843.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CELA2A
Gene Name chymotrypsin-like elastase family, member 2A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000142615
Encoded Proteins
chymotrypsin-like elastase family, member 2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:15456728-15472091
Strand Forward strand
Band p36.21
Transcripts
ENST00000359621 ENSP00000352639
ENST00000459653
ENST00000497590
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0017171 serine hydrolase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region
GO:0036457 keratohyalin granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Pancreatic secretion pathway
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.631866
RefSeq NM_033440
HUGO
OMIM
CCDS CCDS157
HPRD 06495
IMGT
EMBL
GenPept
RNA Seq Atlas