Version 5.4
Mus musculus Gene: Tiprl
Summary
InnateDB Gene IDBG-202595.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tiprl
Gene Name TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040843
Encoded Proteins
IDBP-202597
TIP41, TOR signalling pathway regulator-like (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143155:
TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 612725) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:165214922-165236943
Strand Reverse strand
Band H2.2
Transcripts
ENSMUST00000043235 ENSMUSP00000037514
ENSMUST00000142191
ENSMUST00000156102
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000077 DNA damage checkpoint
GO:0034048 negative regulation of protein phosphatase type 2A activity
Cellular Component
GO:0005737 cytoplasm
GO:0043231 intracellular membrane-bounded organelle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143155
View Gene Order
ENSBTAG00000005393
Not yet available
Cross-References
SwissProt Q8BH58
TrEMBL
UniProt Splice Variant
Entrez Gene 226591
UniGene Mm.21520 Mm.413841
RefSeq NM_145513
OMIM
CCDS CCDS15441
HPRD
IMGT
MGI ID MGI:1915087
MGI Symbol Tiprl
EMBL AK049119 AK049784 AK075774 BC002098 BC058250
GenPept AAH02098 AAH58250 BAC33553 BAC33919 BAC35948
RNA Seq Atlas 226591

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca