Version 5.4
Mus musculus Gene: Creg1
Summary
InnateDB Gene IDBG-202763.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Creg1
Gene Name cellular repressor of E1A-stimulated genes 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000040713
Encoded Proteins
IDBP-202765
cellular repressor of E1A-stimulated genes 1
IDBP-258122
cellular repressor of E1A-stimulated genes 1
IDBP-714433
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143162:
The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:165763746-165775308
Strand Forward strand
Band H2.3
Transcripts
ENSMUST00000040298 ENSMUSP00000041234
ENSMUST00000111432 ENSMUSP00000107060
ENSMUST00000140769 ENSMUSP00000137087
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008134 transcription factor binding
GO:0010181 FMN binding
GO:0016491 oxidoreductase activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0040008 regulation of growth
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005667 transcription factor complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000143162
View Gene Order
ENSBTAG00000008931
Not yet available
Cross-References
SwissProt O88668
TrEMBL J3QP41 K4DI63
UniProt Splice Variant
Entrez Gene 433375
UniGene Mm.294885
RefSeq NM_011804 XM_006496930
OMIM
CCDS CCDS35759
HPRD
IMGT
MGI ID MGI:1344382
MGI Symbol Creg1
EMBL AC124587 AF084524 AK005388 AK010947 AK085844 AK144101 BC027426 CH466520
GenPept AAC34862 AAH27426 BAB23994 BAB27285 BAC39549 BAE25699 EDL39216 EDL39218
RNA Seq Atlas 433375

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca