Version 5.4
Mus musculus Gene: Slc24a5
Summary
InnateDB Gene IDBG-203359.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc24a5
Gene Name solute carrier family 24, member 5
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000035183
Encoded Proteins
IDBP-203361
solute carrier family 24, member 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188467:
This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:125068124-125088677
Strand Forward strand
Band F1
Transcripts
ENSMUST00000070353 ENSMUSP00000063887
ENSMUST00000139615
ENSMUST00000149963
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008273 calcium, potassium:sodium antiporter activity
GO:0015293 symporter activity
Biological Process
GO:0006813 potassium ion transport
GO:0006816 calcium ion transport
GO:0034220 ion transmembrane transport
GO:0035725 sodium ion transmembrane transport
GO:0048022 negative regulation of melanin biosynthetic process
GO:0050896 response to stimulus
GO:0055085 transmembrane transport
Cellular Component
GO:0005802 trans-Golgi network
GO:0016021 integral component of membrane
GO:0042470 melanosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000188467
View Gene Order
ENSBTAG00000004854
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_236234
Sodium/Calcium exchangers pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19320
Sodium/Calcium exchangers pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.330538
RefSeq NM_175034
OMIM
CCDS CCDS38226
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca