Version 5.4
Mus musculus Gene: Nit1
Summary
InnateDB Gene IDBG-204444.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nit1
Gene Name nitrilase 1
Synonyms AI255805; ESTM30; W57327
Species Mus musculus
Ensembl Gene ENSMUSG00000013997
Encoded Proteins
IDBP-258443
nitrilase 1
IDBP-258445
nitrilase 1
IDBP-258447
nitrilase 1
IDBP-535753
nitrilase 1
IDBP-532608
nitrilase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158793:
This gene encodes a member of the nitrilase protein family with homology to bacterial and plant nitrilases, enzymes that cleave nitriles and organic amides to the corresponding carboxylic acids plus ammonia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:171338008-171345646
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000111296 ENSMUSP00000106927
ENSMUST00000111295 ENSMUSP00000106926
ENSMUST00000111289 ENSMUSP00000106920
ENSMUST00000146428
ENSMUST00000141357
ENSMUST00000156856 ENSMUSP00000116835
ENSMUST00000136339
ENSMUST00000148339 ENSMUSP00000119171
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
Biological Process
GO:0006807 nitrogen compound metabolic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000158793
View Gene Order
ENSBTAG00000020153
Not yet available
Cross-References
SwissProt
TrEMBL D3Z2Y2 D3Z3I3
UniProt Splice Variant
Entrez Gene 27045
UniGene Mm.12915 Mm.270139 Mm.440362 Mm.472271
RefSeq NM_001242580 NM_012049 XM_006496866
OMIM
CCDS CCDS35775 CCDS56656
HPRD
IMGT
MGI ID MGI:1350916
MGI Symbol Nit1
EMBL AC084821 AC087229
GenPept
RNA Seq Atlas 27045

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca