InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ncaph

Summary

InnateDB Gene

IDBG-204577.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ncaph

Gene Name

non-SMC condensin I complex, subunit H

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000034906

Encoded Proteins

IDBP-260385

non-SMC condensin I complex, subunit H

IDBP-718364

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121152:
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq, Jul 2008]
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:127103809-127133954

Strand

Reverse strand

Band

Transcripts

ENSMUST00000110387	ENSMUSP00000106017
ENSMUST00000152806
ENSMUST00000146142
ENSMUST00000156625
ENSMUST00000177191
ENSMUST00000175885	ENSMUSP00000135620

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	3 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007076

mitotic chromosome condensation

Cellular Component

GO:0000796	condensin complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0015630	microtubule cytoskeleton
GO:0016020	membrane

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000121152

View Gene Order

ENSBTAG00000012925

Not yet available

Pathways

NETPATH

REACTOME

REACT_249770

Cell Cycle, Mitotic pathway

REACT_188804

Cell Cycle pathway

REACT_241408

M Phase pathway

REACT_256756

Mitotic Prometaphase pathway

REACT_196632

Condensation of Prometaphase Chromosomes pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_150260

Condensation of Prometaphase Chromosomes pathway

REACT_682

Mitotic Prometaphase pathway

REACT_115566

Cell Cycle pathway

REACT_910

M Phase pathway

REACT_152

Cell Cycle, Mitotic pathway

KEGG

INOH

PID NCI

aurora_b_pathway

Aurora B signaling

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.29786 Mm.403934

RefSeq

NM_144818

OMIM

CCDS

CCDS16693

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas