Version 5.4
Homo sapiens Gene: NCAPH
Summary
InnateDB Gene IDBG-61714.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NCAPH
Gene Name non-SMC condensin I complex, subunit H
Synonyms BRRN1; CAP-H
Species Homo sapiens
Ensembl Gene ENSG00000121152
Encoded Proteins
IDBP-61716
non-SMC condensin I complex, subunit H
IDBP-382915
non-SMC condensin I complex, subunit H
IDBP-382917
non-SMC condensin I complex, subunit H
IDBP-382918
non-SMC condensin I complex, subunit H
IDBP-382919
non-SMC condensin I complex, subunit H
IDBP-382920
non-SMC condensin I complex, subunit H
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. [provided by RefSeq, Jul 2008]
This gene encodes a member of the barr gene family and a regulatory subunit of the condensin complex. This complex is required for the conversion of interphase chromatin into condensed chromosomes. The protein encoded by this gene is associated with mitotic chromosomes, except during the early phase of chromosome condensation. During interphase, the protein has a distinct punctate nucleolar localization. Alternatively spliced transcript variants encoding different proteins have been described. [provided by RefSeq, Jul 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:96335787-96373845
Strand Forward strand
Band q11.2
Transcripts
ENST00000240423 ENSP00000240423
ENST00000427946 ENSP00000400774
ENST00000435975 ENSP00000405237
ENST00000456906 ENSP00000401227
ENST00000455200 ENSP00000407308
ENST00000435349 ENSP00000415162
ENST00000477409
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 28 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 28 [view]
Protein-Protein 28 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0000278 mitotic cell cycle
GO:0007076 mitotic chromosome condensation
Cellular Component
GO:0000796 condensin complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034906
View Gene Order
ENSBTAG00000012925
Not yet available
Pathways
NETPATH
REACTOME
REACT_150260
Condensation of Prometaphase Chromosomes pathway
REACT_682
Mitotic Prometaphase pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_152
Cell Cycle, Mitotic pathway
KEGG
INOH
PID NCI
aurora_b_pathway
Aurora B signaling
Cross-References
SwissProt
TrEMBL C9J470
UniProt Splice Variant
Entrez Gene 23397
UniGene Hs.308045
RefSeq NM_001281710 NM_001281711 NM_001281712 NM_015341 XM_005263907 XM_005263908
HUGO HGNC:1112
OMIM 602332
CCDS CCDS2021 CCDS62960
HPRD 03820
IMGT
EMBL AC021188
GenPept
RNA Seq Atlas 23397

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca