Version 5.4
Mus musculus Gene: Tmem127
Summary
InnateDB Gene IDBG-204726.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tmem127
Gene Name transmembrane protein 127
Synonyms 2310003P10Rik; AI314202; AI317350
Species Mus musculus
Ensembl Gene ENSMUSG00000034850
Encoded Proteins
IDBP-204728
transmembrane protein 127
IDBP-627658
transmembrane protein 127
IDBP-627660
transmembrane protein 127
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000135956:
This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:127247908-127261107
Strand Forward strand
Band F1
Transcripts
ENSMUST00000035871 ENSMUSP00000035434
ENSMUST00000174503 ENSMUSP00000133701
ENSMUST00000174288 ENSMUSP00000134629
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008285 negative regulation of cell proliferation
GO:0032007 negative regulation of TOR signaling
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000135956
View Gene Order
ENSBTAG00000015667
Not yet available
Cross-References
SwissProt
TrEMBL G3UXI2
UniProt Splice Variant
Entrez Gene 69470
UniGene Mm.200889 Mm.474083
RefSeq NM_175145 XM_006500136
OMIM
CCDS CCDS16697
HPRD
IMGT
MGI ID MGI:1916720
MGI Symbol Tmem127
EMBL AL845368
GenPept
RNA Seq Atlas 69470

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca