Version 5.4
| Mus musculus Gene: Slamf6 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-204886.6 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | Slamf6 | ||||||
| Gene Name | SLAM family member 6 | ||||||
| Synonyms | KAL1; KAL1b; Ly108; NTB-A; NTBA; SF2000 | ||||||
| Species | Mus musculus | ||||||
| Ensembl Gene | ENSMUSG00000015314 | ||||||
| Encoded Proteins |
SLAM family member 6
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| InnateDB Annotation from Orthologs | |||||||
| Summary |
[Homo sapiens] The SLAM and SAP gene families control innate and adaptive immune responses
[Homo sapiens] SLAM receptors and SAP influence lymphocyte interactions, development and function
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| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162739:
The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, May 2010] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 1:171917537-171943868 | ||||||
| Strand | Forward strand | ||||||
| Band | H3 | ||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH |
TCR pathway
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| REACTOME | |||||||
| KEGG | |||||||
| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | Q9ET39 | ||||||
| TrEMBL | Q18PG5 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 30925 | ||||||
| UniGene | |||||||
| RefSeq | NM_030710 XM_006496884 XM_006496886 XM_006496888 | ||||||
| OMIM | |||||||
| CCDS | CCDS15504 | ||||||
| HPRD | |||||||
| IMGT | |||||||
| MGI ID | MGI:1353620 | ||||||
| MGI Symbol | Slamf6 | ||||||
| EMBL | AB196836 AF248635 AF248636 BC030031 CH466520 | ||||||
| GenPept | AAG01737 AAG01738 AAH30031 BAE96339 EDL39050 | ||||||
| RNA Seq Atlas | 30925 | ||||||