InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ctnnbip1

Summary

InnateDB Gene

IDBG-205218.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ctnnbip1

Gene Name

catenin beta interacting protein 1

Synonyms

1110008O09Rik; 2310001I19Rik; AW457332; Catnbip1; Icat

Species

Mus musculus

Ensembl Gene

ENSMUSG00000028988

Encoded Proteins

IDBP-205220

catenin beta interacting protein 1

IDBP-270339

catenin beta interacting protein 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178585:
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:149518236-149566437

Strand

Forward strand

Band

Transcripts

ENSMUST00000030839	ENSMUSP00000030839
ENSMUST00000105692	ENSMUSP00000101317

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0070016	armadillo repeat domain binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0002528	regulation of vascular permeability involved in acute inflammatory response
GO:0009952	anterior/posterior pattern specification
GO:0016055	Wnt signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:0031333	negative regulation of protein complex assembly
GO:0032091	negative regulation of protein binding
GO:0043392	negative regulation of DNA binding
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
GO:0045657	positive regulation of monocyte differentiation
GO:0045669	positive regulation of osteoblast differentiation
GO:0048662	negative regulation of smooth muscle cell proliferation
GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter
GO:0072201	negative regulation of mesenchymal cell proliferation