Version 5.4
Mus musculus Gene: Cadm3
Summary
InnateDB Gene IDBG-205840.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cadm3
Gene Name cell adhesion molecule 3
Synonyms BIgR; Igsf4b; Necl-1; Necl1; SynCAM3; Tsll1
Species Mus musculus
Ensembl Gene ENSMUSG00000005338
Encoded Proteins
IDBP-205842
cell adhesion molecule 3
IDBP-258589
cell adhesion molecule 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000162706:
IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:173334254-173367695
Strand Reverse strand
Band H3
Transcripts
ENSMUST00000005470 ENSMUSP00000005470
ENSMUST00000111220 ENSMUSP00000106851
ENSMUST00000136540
ENSMUST00000157032
ENSMUST00000126963
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007156 homophilic cell adhesion
GO:0007157 heterophilic cell-cell adhesion
GO:0008104 protein localization
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000162706
View Gene Order
ENSBTAG00000003217
Not yet available
Pathways
NETPATH
REACTOME
REACT_248094
Cell-cell junction organization pathway
REACT_230395
Adherens junctions interactions pathway
REACT_245004
Nectin/Necl trans heterodimerization pathway
REACT_241978
Cell junction organization pathway
REACT_223082
Cell-Cell communication pathway
KEGG
mmu04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19268
Nectin/Necl trans heterodimerization pathway
REACT_19195
Adherens junctions interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_19331
Cell-cell junction organization pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL K4DI58
UniProt Splice Variant
Entrez Gene 94332
UniGene Mm.330524 Mm.405431
RefSeq NM_053199
OMIM
CCDS CCDS15528
HPRD
IMGT
MGI ID MGI:2137858
MGI Symbol Cadm3
EMBL AC084073 AC087781 CH466520
GenPept EDL38990
RNA Seq Atlas 94332

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca