Version 5.4
Homo sapiens Gene: CADM3
Summary
InnateDB Gene IDBG-103868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CADM3
Gene Name cell adhesion molecule 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000162706
Encoded Proteins
IDBP-103870
cell adhesion molecule 3
IDBP-103872
cell adhesion molecule 3
IDBP-389196
cell adhesion molecule 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary IGSF4B is a brain-specific protein related to the calcium-independent cell-cell adhesion molecules known as nectins (see PVRL3; MIM 607147) (Kakunaga et al., 2005 [PubMed 15741237]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:159171609-159203313
Strand Forward strand
Band q23.2
Transcripts
ENST00000368125 ENSP00000357107
ENST00000368124 ENSP00000357106
ENST00000416746 ENSP00000387802
ENST00000497636
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0007156 homophilic cell adhesion
GO:0007157 heterophilic cell-cell adhesion
GO:0008104 protein localization
GO:0034329 cell junction assembly
GO:0034332 adherens junction organization
GO:0045216 cell-cell junction organization
Cellular Component
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000005338
View Gene Order
ENSBTAG00000003217
Not yet available
Pathways
NETPATH
REACTOME
REACT_19268
Nectin/Necl trans heterodimerization pathway
REACT_19195
Adherens junctions interactions pathway
REACT_111155
Cell-Cell communication pathway
REACT_20676
Cell junction organization pathway
REACT_19331
Cell-cell junction organization pathway
KEGG
hsa04514
Cell adhesion molecules (CAMs) pathway
INOH
PID NCI
Cross-References
SwissProt Q8N126
TrEMBL
UniProt Splice Variant
Entrez Gene 57863
UniGene Hs.365689
RefSeq NM_021189 NM_001127173
HUGO HGNC:17601
OMIM 609743
CCDS CCDS1182 CCDS44251
HPRD 13733
IMGT
EMBL AF062733 AF363367 AF529206 AK001560 AL035403 AY046418 AY358332
GenPept AAD17540 AAL02143 AAM60749 AAN75603 AAQ88698 BAA91756 CAB56227
RNA Seq Atlas 57863

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca