Version 5.4
Mus musculus Gene: Stag3
Summary
InnateDB Gene IDBG-206116.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Stag3
Gene Name stromal antigen 3
Synonyms SA-2
Species Mus musculus
Ensembl Gene ENSMUSG00000036928
Encoded Proteins
IDBP-206118
stromal antigen 3
IDBP-535063
stromal antigen 3
IDBP-535966
stromal antigen 3
IDBP-538783
stromal antigen 3
IDBP-531971
stromal antigen 3
IDBP-538140
stromal antigen 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000066923:
The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:138280240-138312393
Strand Forward strand
Band G2
Transcripts
ENSMUST00000048028 ENSMUSP00000040945
ENSMUST00000160729 ENSMUSP00000124170
ENSMUST00000161113
ENSMUST00000159483
ENSMUST00000162245 ENSMUSP00000125523
ENSMUST00000161691 ENSMUSP00000125290
ENSMUST00000161615
ENSMUST00000160849 ENSMUSP00000125376
ENSMUST00000159189 ENSMUSP00000124959
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007065 male meiosis sister chromatid cohesion
GO:0007066 female meiosis sister chromatid cohesion
Cellular Component
GO:0000775 chromosome, centromeric region
GO:0000794 condensed nuclear chromosome
GO:0000795 synaptonemal complex
GO:0000800 lateral element
GO:0000802 transverse filament
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0030893 meiotic cohesin complex
GO:0034991 nuclear meiotic cohesin complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000066923
View Gene Order
ENSBTAG00000010496
Not yet available
Pathways
NETPATH
REACTOME
REACT_75800
Meiotic Synapsis pathway
REACT_200794
Mus musculus biological processes pathway
REACT_198626
Meiotic synapsis pathway
REACT_188804
Cell Cycle pathway
REACT_198624
Meiosis pathway
KEGG
mmu04114
Oocyte meiosis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75792
Meiotic synapsis pathway
REACT_115566
Cell Cycle pathway
REACT_111183
Meiosis pathway
KEGG
hsa04114
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.285609
RefSeq NM_016964 XM_006504596 XM_006504597 XM_006504599 XM_006504600 XM_006504601
OMIM
CCDS CCDS39344
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca