Version 5.4
Mus musculus Gene: Mixl1
Summary
InnateDB Gene IDBG-207256.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mixl1
Gene Name Mix1 homeobox-like 1 (Xenopus laevis)
Synonyms Mm1; Mml
Species Mus musculus
Ensembl Gene ENSMUSG00000026497
Encoded Proteins
IDBP-207258
Mix1 homeobox-like 1 (Xenopus laevis)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000185155:
Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:180693043-180697034
Strand Reverse strand
Band H4
Transcripts
ENSMUST00000027778 ENSMUSP00000027778
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 10 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000987 core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 RNA polymerase II transcription factor binding
GO:0001103 RNA polymerase II repressing transcription factor binding
GO:0001190 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001706 endoderm formation
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0007369 gastrulation
GO:0007492 endoderm development
GO:0007507 heart development
GO:0030097 hemopoiesis
GO:0035987 endodermal cell differentiation
GO:0042074 cell migration involved in gastrulation
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048565 digestive tract development
GO:1901533 negative regulation of hematopoietic progenitor cell differentiation
GO:2000382 positive regulation of mesoderm development
Cellular Component
GO:0000790 nuclear chromatin
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000185155
View Gene Order
ENSBTAG00000002139
Not yet available
Cross-References
SwissProt Q9WUI0
TrEMBL
UniProt Splice Variant
Entrez Gene 27217
UniGene Mm.103647
RefSeq NM_013729 XM_006496871
OMIM
CCDS CCDS15571
HPRD
IMGT
MGI ID MGI:1351322
MGI Symbol Mixl1
EMBL AF135063 AF154573 AF201959 AF447591 BC099876 BC099877
GenPept AAD25543 AAF08314 AAH99876 AAH99877 AAK59867 AAM77218
RNA Seq Atlas 27217

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca