Version 5.4
Mus musculus Gene: Slc29a4
Summary
InnateDB Gene IDBG-207381.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc29a4
Gene Name solute carrier family 29 (nucleoside transporters), member 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000050822
Encoded Proteins
IDBP-207383
solute carrier family 29 (nucleoside transporters), member 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164638:
This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:142702101-142722490
Strand Forward strand
Band G2
Transcripts
ENSMUST00000058418 ENSMUSP00000059896
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005337 nucleoside transmembrane transporter activity
GO:0008504 monoamine transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0015844 monoamine transport
GO:1901642 nucleoside transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000164638
View Gene Order
ENSBTAG00000007772
Not yet available
Pathways
NETPATH
REACTOME
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_232951
Transport of vitamins, nucleosides, and related molecules pathway
REACT_247934
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1206
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane pathway
REACT_22285
Transport of vitamins, nucleosides, and related molecules pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8R139
TrEMBL
UniProt Splice Variant
Entrez Gene 243328
UniGene Mm.125942
RefSeq NM_146257 XM_006504706 XM_006504707
OMIM
CCDS CCDS39364
HPRD
IMGT
MGI ID MGI:2385330
MGI Symbol Slc29a4
EMBL BC025599
GenPept AAH25599
RNA Seq Atlas 243328

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca