Version 5.4
Mus musculus Gene: Fermt1
Summary
InnateDB Gene IDBG-207575.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fermt1
Gene Name fermitin family homolog 1 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000027356
Encoded Proteins
IDBP-207577
fermitin family homolog 1 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000101311:
This gene encodes a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. The encoded protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix. Mutations in this gene have been linked to Kindler syndrome. [provided by RefSeq, Dec 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:132904389-132945906
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000038280 ENSMUSP00000047616
ENSMUST00000134937
ENSMUST00000144342
ENSMUST00000143981
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0007155 cell adhesion
GO:0043616 keratinocyte proliferation
GO:0051546 keratinocyte migration
GO:0090162 establishment of epithelial cell polarity
Cellular Component
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0030054 cell junction
GO:0031941 filamentous actin
GO:0032587 ruffle membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000101311
View Gene Order
ENSBTAG00000020465
Not yet available
Cross-References
SwissProt P59113
TrEMBL
UniProt Splice Variant
Entrez Gene 241639
UniGene Mm.209784
RefSeq NM_198029 XM_006499507
OMIM
CCDS CCDS38248
HPRD
IMGT
MGI ID MGI:2443583
MGI Symbol Fermt1
EMBL AK050804 AL831763 BC029093 BC042792
GenPept AAH29093 BAC34417 CAM20382
RNA Seq Atlas 241639

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca