Version 5.4
Mus musculus Gene: Gp2
Summary
InnateDB Gene IDBG-207909.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gp2
Gene Name glycoprotein 2 (zymogen granule membrane)
Synonyms 2310037I18Rik; AV060639
Species Mus musculus
Ensembl Gene ENSMUSG00000030954
Encoded Proteins
IDBP-207911
glycoprotein 2 (zymogen granule membrane)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21468225
Gp2 on M cells (specialized epithelial antigen-transporting cells) functions as an uptake receptor for a subset of commensal and pathogenic bacteria. Gp2 interacts with type 1 pilus of gram-negative enterobacilli such as E. coli and Salmonella enterica.
InnateDB Annotation from Orthologs
Summary
PMID 21468225
[Homo sapiens] GP2 on M cells (specialized epithelial antigen-transporting cells) functions as an uptake receptor for a subset of commensal and pathogenic bacteria. GP2 interacts with type 1 pilus of gram-negative enterobacilli such as E. coli and Salmonella enterica. (Demonstrated in murine model)
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169347:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:119442544-119459272
Strand Reverse strand
Band F2
Transcripts
ENSMUST00000033255 ENSMUSP00000033255
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
Biological Process
GO:0002412 antigen transcytosis by M cells in mucosal-associated lymphoid tissue
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0016324 apical plasma membrane
GO:0031225 anchored component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000169347
View Gene Order
ENSBTAG00000006263
Not yet available
Cross-References
SwissProt Q9D733
TrEMBL Q9CV52
UniProt Splice Variant
Entrez Gene 67133
UniGene Mm.46403
RefSeq NM_025989 XM_006508121
OMIM
CCDS CCDS21779
HPRD
IMGT
MGI ID MGI:1914383
MGI Symbol Gp2
EMBL AK009558 AK009661
GenPept BAB26357 BAB26423
RNA Seq Atlas 67133

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca