Version 5.4
Bos taurus Gene: BT.67549
Summary
InnateDB Gene IDBG-637931.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.67549
Gene Name pancreatic secretory granule membrane major glycoprotein GP2 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006263
Encoded Proteins
IDBP-689964
pancreatic secretory granule membrane major glycoprotein GP2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 21468225
[Homo sapiens] GP2 on M cells (specialized epithelial antigen-transporting cells) functions as an uptake receptor for a subset of commensal and pathogenic bacteria. GP2 interacts with type 1 pilus of gram-negative enterobacilli such as E. coli and Salmonella enterica. (Demonstrated in murine model)
PMID 21468225
[Mus musculus] Gp2 on M cells (specialized epithelial antigen-transporting cells) functions as an uptake receptor for a subset of commensal and pathogenic bacteria. Gp2 interacts with type 1 pilus of gram-negative enterobacilli such as E. coli and Salmonella enterica.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169347:
Gene Information
Type Protein coding
Genomic Location Chromosome 25:18102959-18118225
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008217 ENSBTAP00000008217
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003823 antigen binding
Biological Process
GO:0002412 antigen transcytosis by M cells in mucosal-associated lymphoid tissue
Cellular Component
GO:0005576 extracellular region
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000169347
View Gene Order
ENSMUSG00000030954
View Gene Order
Cross-References
SwissProt
TrEMBL F1N726
UniProt Splice Variant
Entrez Gene 531420
UniGene Bt.2278 Bt.67549
RefSeq NM_001075950 XM_005224746 XM_005224747
HUGO HGNC:4441
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02057632
GenPept
RNA Seq Atlas 531420

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca