InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Snrpb2

Summary

InnateDB Gene

IDBG-208295.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Snrpb2

Gene Name

U2 small nuclear ribonucleoprotein B

Synonyms

2810052G09Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000008333

Encoded Proteins

IDBP-208297

U2 small nuclear ribonucleoprotein B

IDBP-532506

U2 small nuclear ribonucleoprotein B

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000125870:
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A\'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:143063039-143072853

Strand

Forward strand

Band

Transcripts

ENSMUST00000008477	ENSMUSP00000008477
ENSMUST00000139114
ENSMUST00000126763	ENSMUSP00000120137
ENSMUST00000127760
ENSMUST00000134091

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0005515	protein binding
GO:0017069	snRNA binding

Biological Process

GO:0000398

mRNA splicing, via spliceosome

Cellular Component

GO:0005634	nucleus
GO:0005681	spliceosomal complex
GO:0005730	nucleolus
GO:0071013	catalytic step 2 spliceosome

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000125870

View Gene Order

ENSBTAG00000027506

Not yet available

Pathways

NETPATH

REACTOME

REACT_249110

mRNA Splicing pathway

REACT_233572

Gene Expression pathway

REACT_260226

mRNA Splicing - Major Pathway pathway

REACT_233950

Processing of Capped Intron-Containing Pre-mRNA pathway

KEGG

mmu03040

Spliceosome pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_467

mRNA Splicing - Major Pathway pathway

REACT_125

Processing of Capped Intron-Containing Pre-mRNA pathway

REACT_1735

mRNA Splicing pathway

REACT_71

Gene Expression pathway

KEGG

hsa03040

Spliceosome pathway

INOH

PID NCI

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

Mm.1323 Mm.407941 Mm.443514

RefSeq

NM_021335

OMIM

CCDS

CCDS16808

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas