Version 5.4
Homo sapiens Gene: SNRPB2
Summary
InnateDB Gene IDBG-55609.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNRPB2
Gene Name small nuclear ribonucleoprotein polypeptide B
Synonyms Msl1
Species Homo sapiens
Ensembl Gene ENSG00000125870
Encoded Proteins
IDBP-55611
small nuclear ribonucleoprotein polypeptide B
IDBP-55613
small nuclear ribonucleoprotein polypeptide B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A\'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:16729961-16742563
Strand Forward strand
Band p12.1
Transcripts
ENST00000246071 ENSP00000246071
ENST00000377943 ENSP00000367178
ENST00000478522
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
Experimentally validated
Total 49 [view]
Protein-Protein 49 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0017069 snRNA binding
Biological Process
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0010467 gene expression
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005686 U2 snRNP
GO:0005730 nucleolus
GO:0071013 catalytic step 2 spliceosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000008333
View Gene Order
ENSBTAG00000027506
Not yet available
Pathways
NETPATH
REACTOME
REACT_467
mRNA Splicing - Major Pathway pathway
REACT_125
Processing of Capped Intron-Containing Pre-mRNA pathway
REACT_1735
mRNA Splicing pathway
REACT_71
Gene Expression pathway
KEGG
hsa03040
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_003092 NM_198220
HUGO
OMIM
CCDS CCDS13123
HPRD 04628
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca