Mus musculus Gene: Abcc3
Summary
InnateDB Gene IDBG-208859.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Abcc3
Gene Name ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Synonyms 1700019L09Rik; ABC31; MLP2; MOAT-D; MRP3
Species Mus musculus
Ensembl Gene ENSMUSG00000020865
Encoded Proteins
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108846:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:94343295-94392997
Strand Reverse strand
Band D
Transcripts
ENSMUST00000021231 ENSMUSP00000021231
ENSMUST00000140985
ENSMUST00000155253
ENSMUST00000151124
ENSMUST00000126566
ENSMUST00000178136 ENSMUSP00000136343
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005215 transporter activity
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0017111 nucleoside-triphosphatase activity
GO:0042626 ATPase activity, coupled to transmembrane movement of substances
Biological Process
GO:0006200 ATP catabolic process
GO:0006810 transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Recycling of bile acids and salts pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Transmembrane transport of small molecules pathway
ABC-family proteins mediated transport pathway
Bile acid and bile salt metabolism pathway
KEGG
ABC transporters pathway
Bile secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
ABC-family proteins mediated transport pathway
Recycling of bile acids and salts pathway
Transmembrane transport of small molecules pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Metabolism pathway
KEGG
ABC transporters pathway
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_029600 XM_006534428
OMIM
CCDS CCDS25254
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas