InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ABCC3

Summary

InnateDB Gene

IDBG-638500.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABCC3

Gene Name

canalicular multispecific organic anion transporter 2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000020070

Encoded Proteins

IDBP-690577

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108846:
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:36676547-36724513

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000026744

ENSBTAP00000026744

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0005215	transporter activity
GO:0005524	ATP binding
GO:0016887	ATPase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0042626	ATPase activity, coupled to transmembrane movement of substances