Version 5.4
Mus musculus Gene: Aqp8
Summary
InnateDB Gene IDBG-209160.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Aqp8
Gene Name aquaporin 8
Synonyms AI255744; AQP-8
Species Mus musculus
Ensembl Gene ENSMUSG00000030762
Encoded Proteins
IDBP-209162
aquaporin 8
IDBP-209164
aquaporin 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000103375:
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008]
Aquaporin 8 (AQP8) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 8 mRNA is found in pancreas and colon but not other tissues. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:123462294-123468003
Strand Forward strand
Band F3
Transcripts
ENSMUST00000033023 ENSMUSP00000033023
ENSMUST00000098056 ENSMUSP00000095664
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0015250 water channel activity
Biological Process
GO:0006810 transport
GO:0006833 water transport
GO:0015722 canalicular bile acid transport
GO:0071320 cellular response to cAMP
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0043231 intracellular membrane-bounded organelle
GO:0045177 apical part of cell
GO:0046691 intracellular canaliculus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000103375
View Gene Order
ENSBTAG00000020184
Not yet available
Pathways
NETPATH
REACTOME
REACT_188957
Cellular responses to stress pathway
REACT_189141
Detoxification of Reactive Oxygen Species pathway
REACT_226335
Aquaporin-mediated transport pathway
REACT_259079
Passive transport by Aquaporins pathway
REACT_253400
Transmembrane transport of small molecules pathway
KEGG
mmu04976
Bile secretion pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_23826
Passive transport by Aquaporins pathway
REACT_120956
Cellular responses to stress pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_172715
Detoxification of Reactive Oxygen Species pathway
REACT_23887
Aquaporin-mediated transport pathway
KEGG
hsa04976
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.273175
RefSeq NM_001109045 NM_007474
OMIM
CCDS CCDS72038
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca