Mus musculus Gene: Tac4
Summary
InnateDB Gene IDBG-209534.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tac4
Gene Name tachykinin 4
Synonyms AW489379; PPT-C
Species Mus musculus
Ensembl Gene ENSMUSG00000020872
Encoded Proteins
tachykinin 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000176358:
This gene is a member of the tachykinin family of neurotransmitter-encoding genes. Tachykinin proteins are cleaved into small, secreted peptides that activate members of a family of receptor proteins. The products of this gene preferentially activate tachykinin receptor 1, and are thought to regulate peripheral endocrine and paracrine functions including blood pressure, the immune system, and endocrine gland secretion. The products of this gene lack a dibasic cleavage site found in other tachykinin proteins. Consequently, the nature of the cleavage products generated in vivo remains to be determined. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:95261529-95269265
Strand Forward strand
Band D
Transcripts
ENSMUST00000021242 ENSMUSP00000021242
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
Biological Process
GO:0007217 tachykinin receptor signaling pathway
GO:0008217 regulation of blood pressure
GO:0043303 mast cell degranulation
GO:0046878 positive regulation of saliva secretion
Cellular Component
GO:0005576 extracellular region
GO:0042629 mast cell granule
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
Cross-References
SwissProt Q99N14
TrEMBL
UniProt Splice Variant
Entrez Gene 93670
UniGene Mm.40085
RefSeq NM_053093
OMIM
CCDS CCDS25274
HPRD
IMGT
MGI ID MGI:1931130
MGI Symbol Tac4
EMBL AF235035 AF515827 AL627222 BC119426
GenPept AAI19427 AAK15025 AAP30873 CAI24806
RNA Seq Atlas 93670