Version 5.4
| Mus musculus Gene: Slx1b | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-209733.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Slx1b | ||||||||
| Gene Name | SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae) | ||||||||
| Synonyms | 1110030E23Rik; 2410170E21Rik; 4833422P03Rik; AI853643; Giyd1; Giyd2 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000059772 | ||||||||
| Encoded Proteins |
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181625:
This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A3 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3) gene. [provided by RefSeq, Nov 2010] This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene. [provided by RefSeq, Nov 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 7:126689468-126695784 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | F3 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Mm.280573 | ||||||||
| RefSeq | NM_029420 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS21838 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | |||||||||
| MGI Symbol | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||