Mus musculus Gene: Doc2a
Summary
InnateDB Gene IDBG-209883.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Doc2a
Gene Name double C2, alpha
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000052301
Encoded Proteins
double C2, alpha
double C2, alpha
double C2, alpha
double C2, alpha
double C2, alpha
double C2, alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000149927:
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. [provided by RefSeq, Jul 2008]
There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:126847416-126852705
Strand Forward strand
Band F3
Transcripts
ENSMUST00000064110 ENSMUSP00000070119
ENSMUST00000141805 ENSMUSP00000118143
ENSMUST00000152406
ENSMUST00000152051 ENSMUSP00000123483
ENSMUST00000147257 ENSMUSP00000123143
ENSMUST00000139174 ENSMUSP00000117376
ENSMUST00000137873 ENSMUSP00000119779
ENSMUST00000176771 ENSMUSP00000135114
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005515 protein binding
GO:0005544 calcium-dependent phospholipid binding
Biological Process
GO:0016079 synaptic vesicle exocytosis
GO:0017158 regulation of calcium ion-dependent exocytosis
Cellular Component
GO:0005764 lysosome
GO:0030054 cell junction
GO:0030672 synaptic vesicle membrane
GO:0043005 neuron projection
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL D3YZ51 D3Z126 D3Z1K1
UniProt Splice Variant
Entrez Gene 13446
UniGene Mm.490525
RefSeq NM_010069
OMIM
CCDS CCDS21847
HPRD
IMGT
MGI ID MGI:109446
MGI Symbol Doc2a
EMBL AC124505
GenPept
RNA Seq Atlas 13446